Comparison of PD-MCI and DLB-MCI criteria and correlates

 
   Lead Investigator:    Jon Toledo
   Institution      :    University of Florida
   E-Mail           :    tintinjb@gmail.com
   Proposal ID      :    1538



   Proposal Description:
   The clinical distinction between Parkinson's disease dementia (PDD) and  dementia with Lewy bodies (DLB) has been defined by the timing of the dementia   and motor onset in patients along their disease course. Recently, DLB prodromal  criteria have been released and therefore, a dementia diagnosis is not needed     for the prodromal DLB diagnosis. To evaluate the clinical profile of DLB in the  predementia stages we propose and analysis of DLB-MCI and PD-MCI subjects in     the NACC cohort. The goal is to evaluate whether individuals clinically           diagnosed with MCI due to Lewy body disease in NACC meet the relevant MCI         criteria and to compare the demographic characteristics, neuropsychiatric and     cognitive profiles, and rate of progression of PD-MCI versus DLB-MCI subjects.